These tools can help you find
the answers you need

Christy D. and Heidi S.
MS LifeLines Ambassadors,
living with relapsing MS

Doctor Conversation Starter

Being able to talk to your healthcare provider is very important. It helps you make the most out of every visit and feel like you truly are a team in your care. The Doctor Conversation Starter has simple steps to help strengthen the communication between you and your healthcare provider.

Get the Doctor Conversation Starter

MS Symptom Checklist

Your doctor will want to know what symptoms you’ve experienced since your last visit. Knowing the answers to our Symptom Checklist questions will help you tell the “story” of your symptom(s) and guide your treatment. Be sure to bring it with you to your next appointment.

Get the MS Symptom Checklist

Sleep Diary

Our seven-day Sleep Diary can help you and your doctor discuss whether your sleep quality is a factor in your fatigue. Answering the specific questions in the diary is more helpful than general statements such as, “I’m not sleeping great.” You can fill it out on your computer or by hand, then bring it to your next appointment.

Get the Sleep Diary

Facebook Page

The MS LifeLines page on Facebook is a community of people focused on life with relapsing MS. Whether you have MS or love someone who does, come here to find inspiration, tips, humor, information, and education. We are over 100,000 strong and growing. Find strength in our numbers.

Visit us on Facebook

YouTube Channel

Life can be unpredictable when you have relapsing MS. That’s why the official MS LifeLines YouTube channel has videos to help you find answers to treatment questions, inspire you with stories of people living with relapsing MS, and help answer your questions about life with MS. Subscribe to our channel and stay up to date.

See all the MS LifeLines videos

Check My Meds App

Check My Meds is a free, easy-to-use application for your smartphone or tablet that puts information right at your fingertips. We created the app to help you and your healthcare provider verify the authenticity of serial numbers on Rebif ® (interferon beta-1a) packages. Download it now on iTunes or at Google Play.

Download App Store     Get on Google Play

Download the PDF to find out more

MS LifeLines Ambassadors are sponsored by EMD Serono, Inc.


Rebif ® (interferon beta-1a) is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS.

Important Safety Information

Before beginning treatment, you should discuss the potential benefits and risks associated with Rebif with your healthcare provider.

Rebif can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking Rebif.

  • Behavioral health problems, including depression and suicidal thoughts. You may have mood problems including depression (feeling hopeless or feeling bad about yourself), and thoughts of hurting yourself or suicide
  • Liver problems or worsening of liver problems, including liver failure. Symptoms may include nausea, loss of appetite, tiredness, dark colored urine and pale stools, yellowing of your skin or the white part of your eye, bleeding more easily than normal, confusion, and sleepiness. During your treatment with Rebif you will need to see your healthcare provider regularly and have regular blood tests to check for side effects
  • Serious allergic and skin reactions. Symptoms may include itching, swelling of your face, eyes, lips, tongue or throat, trouble breathing, anxiousness, feeling faint, skin rash, hives, sores in your mouth, or skin blisters and peels
  • Injection site problems. Symptoms at the injection site may include redness, pain, swelling, color changes (blue or black), and drainage of fluid
  • Blood problems. Rebif can affect your bone marrow and cause low red and white blood cell and platelet counts. In some people, these blood cell counts may fall to dangerously low levels. If your blood cell counts become very low, you can get infections and problems with bleeding and bruising. Your healthcare provider may ask you to have regular blood tests to check for blood problems
  • Seizures. Some people have had seizures while taking Rebif

Rebif will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS.

Do not take Rebif if you are allergic to interferon beta, human albumin, or any of the ingredients in Rebif.

Before you take Rebif, tell your healthcare provider if you have or have had any of the following conditions:

  • mental illness, including depression and suicidal behavior
  • liver problems, bleeding problems or blood clots, low blood cell counts, seizures (epilepsy), or thyroid problems
  • you drink alcohol
  • you are pregnant or plan to become pregnant. It is not known if Rebif will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with Rebif
  • you are breastfeeding or plan to breastfeed. It is not known if Rebif passes into your breast milk. You and your healthcare provider should decide if you will use Rebif or breastfeed. You should not do both

Tell your healthcare provider about all medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effects of Rebif include:

  • flu-like symptoms. You may have flu-like symptoms when you first start taking Rebif. You may be able to manage these flu-like symptoms by taking over-the-counter pain and fever reducers. For many people, these symptoms lessen or go away over time. Symptoms may include muscle aches, fever, tiredness, and chills
  • stomach pain
  • change in liver blood tests

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Rebif. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects.

Refer to the Instructions for Use that comes with the Rebif ® Rebidose® (interferon beta-1a) autoinjector.

This information is not intended to replace discussions with your doctor. For additional information about Rebif, please consult the Prescribing Information and Medication Guide and talk to your doctor. You can also visit or call, toll-free, 1-877-447-3243. Rebif is available by prescription only.

Rebif, Rebif Rebidose, Rebiject II, MS LifeLines, and the Rebif logo are registered trademarks of EMD Serono, Inc. or its affiliates.

Brought to you by EMD Serono, Inc., the marketer of Rebif in the US.

This information is intended only for residents of the United States.